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Symbol
Name
ID

Ace
angiotensin I converting enzyme
MGI:87874

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Eclampsia	Maternal hypertension	Preeclampsia	Abnormal reproductive system morphology	Clitoral hypertrophy	Orchitis	Epididymitis	Polycystic ovaries	Genital ulcers
Disease(s) Associated with ACE	Eclampsia	Maternal hypertension	Preeclampsia	Abnormal reproductive system morphology	Clitoral hypertrophy	Orchitis	Epididymitis	Polycystic ovaries	Genital ulcers
Behcet's disease
familial mediterranean fever
pre-eclampsia
sarcoidosis

Mouse Phenotypes		reproductive system phenotype	impaired sperm migration in female genital tract	decreased litter size	reduced male fertility	impaired fertilization	decreased fertilization frequency	impaired binding of sperm to zona pellucida
Availability	Mouse Genotype	reproductive system phenotype	impaired sperm migration in female genital tract	decreased litter size	reduced male fertility	impaired fertilization	decreased fertilization frequency	impaired binding of sperm to zona pellucida
	Ace^tm1Keb/Ace^tm1Keb
	Ace^tm1Mcf/Ace^tm1Mcf	*
	Ace^tm1Unc/Ace^tm1Unc	*
	Ace^tm2Keb/Ace^tm2Keb
	Ace^tm2Unc/Ace^tm2Unc	*
	Ace^tm1Unc/Ace⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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